4,5-Diaminopicolinic Acid Methyl Ester

4,5-Diaminopicolinic Acid Methyl Ester - Names and Identifiers

Name	2-Pyridinecarboxylic acid, 4,5-diamino-, methyl ester
Synonyms	Methyl 4,5-diaMinopicolinate Methyl 4,5-diaminopicolinate 4,5-Diaminopicolinic Acid Methyl Ester 4,5-Diaminopicolinic acid methyl ester Methyl 4,5-Diaminopyridine-2-carboxylate 4,5-diaMino-2-PyridinecarboxylicacidMethylester 4,5-Diaminopyridine-2-carboxylic acid methyl ester 2-PYRIDINECARBOXYLIC ACID, 4,5-DIAMINO-,METHYL ESTER 2-Pyridinecarboxylic acid, 4,5-diamino-, methyl ester
CAS	850689-13-3
InChI	InChI=1S/C7H9N3O2/c1-12-7(11)6-2-4(8)5(9)3-10-6/h2-3H,9H2,1H3,(H2,8,10)

4,5-Diaminopicolinic Acid Methyl Ester - Physico-chemical Properties

Molecular Formula	C7H9N3O2
Molar Mass	167.17
Density	1.336
Boling Point	427.6±40.0 °C(Predicted)
pKa	5.29±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

4,5-Diaminopicolinic Acid Methyl Ester - Introduction

2-Pyridinecarboxylic acid, 4,5-diamino-, methyl ester (also known as 2-Pyridinecarboxylic acid, 4,5-diamino-, methyl ester) is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Chemical formula: C8H10N4O2
-Molecular weight: 194.19g/mol
-Appearance: White crystalline solid
-Melting point: 130-133°C
-Solubility: Slightly soluble in water, soluble in alcohol and ether
-nature: combustible, with smoky flavor

Use:
2-Pyridinecarboxylic acid, 4,5-diamino-, methyl ester is often used in organic synthesis to prepare other compounds, especially pyridine derivatives. It can be used as a pharmaceutical intermediate, such as a synthetic precursor for some anti-tumor and anti-biologically active compounds.

Preparation Method:
2-Pyridinecarboxylic acid, 4,5-diamino-, methyl ester can be prepared by the following steps:
1.2-pyridinecarboxylic acid is reacted with tetramethyldiazamine to obtain methylene 2-pyridinecarboxylate.
2. Reaction of methylene 2-picolinate with methyl carbamate to give 2-Pyridinecarboxylic acid, 4,5-diamino-, methyl ester.

Safety Information:
- 2-Pyridinecarboxylic acid, 4,5-diamino-, methyl ester is a chemical. Care should be taken to follow appropriate laboratory safety procedures and avoid contact with skin and eyes.
-Wear appropriate personal protective equipment such as gloves, protective glasses and laboratory coats during operation.
-It should be stored in a sealed container, away from fire and combustibles.
-If accidental contact or inhalation, please clean or seek medical assistance.

Last Update：2024-04-09 02:00:48